[P2P-F] darpa's living foundries

Tue Jun 14 14:17:07 CEST 2011

   Bryan Bishop <kanzure at gmail.com> Jun 07 02:26PM -0500
^<?ui=2&view=bsp&ver=ohhl4rw8mbn4#1306f1a96c29344f_digest_top>

   https://www.fbo.gov/spg/ODA/DARPA/CMO/DARPA-SN-11-44/listing.html

   Synopsis:
   Added: Jun 03, 2011 4:42 pm
   Special Notice (SN) DARPA-SN-11-44
   SUBJECT: Living Foundries Industry Day
   DATE: June 28, 2011
   REGISTRATION DEADLINE: June 21, 2011
   Registration Website: https://safe.sysplan.com/mto/livingfoundries
   TECHNICAL POC: Dr. Alicia Jackson, DARPA/MTO

   Living Foundries Industry Day, DARPA-SN-11-44

   The Microsystems Technology Office (MTO) of the Defense Advanced Research
   Projects Agency (DARPA) is sponsoring an Industry Day for "Living
   Foundries," a new DARPA program. The goal of the Living Foundries program
   is
   to apply an engineering framework to biology to harness its use as a
   technology and drive its advance as a manufacturing platform. In turning
   biological production into an engineering space where the only limit is
   the
   creativity of the designer, Living Foundries aims to enable on-demand
   production of new and high-value materials, devices and capabilities for
   the
   Department of Defense and establish a new manufacturing capability for
   the
   United States.

   Because of the multidisciplinary nature of Living Foundries, DARPA is
   looking to engage the wider research community from fields both outside
   and
   inside the biological sciences to develop new ideas, approaches and tools
   to
   overcome current limitations and to create revolutionary capabilities.

   Current, primitive examples of engineering biology rely on an ad hoc,
   laborious, trial-and-error process, wherein one successful project does
   not
   inform subsequent, new designs. This approach combined with the
   complexity
   of biological systems restricts current, one-off efforts to modifying
   only a
   small set of genes and constructing simple, isolated genetic circuits and
   metabolic pathways. Consequently, we are limited to producing only a
   small
   fraction of the vast number of possible chemicals, materials, and living
   systems that would be enabled by the ability to truly engineer biology.
   Through an engineering-driven approach to biology, Living Foundries aims
   to
   create a rapid, reliable manufacturing capability where multiple cellular
   functions can be fabricated, mixed and matched on demand and the whole
   system controlled by integrated circuitry, opening up the full space of
   biologically produced materials and systems. Key to success will be the
   democratization of the biological design and manufacturing process,
   breaking
   open the field to those outside the biological sciences.

   In order to achieve the vision of Living Foundries, new tools,
   technologies
   and methodologies must be developed to transform biology into an
   engineering
   practice, decoupling design from fabrication and speeding the biological
   design, build, test cycle. These include: design tools that span from
   high-level description to fabrication in cells; modular genetic parts
   that
   allow a combination of systems to be designed and reproducibly assembled;
   methods for developing and fine-tuning new genetic parts and systems;
   well-understood test platforms, "cell-like" systems and chassis that
   readily
   integrate new genetic designs in a predictable fashion; next generation
   DNA
   synthesis and assembly techniques; and tools that allow for routine
   system
   characterization and debugging, among others. Further, these
   technological
   advances and innovations must be integrated to prove-out and push the
   boundaries of biological design towards the ultimate vision of
   point-of-use,
   on-demand, mass-customization biological manufacturing.

   The Industry Day will be held at the Capitol Conference Center in
   Arlington,
   VA on June 28, 2011. Directions to the Capital Conference Center can be
   found at http://www.thecapitalconferencecenter.com/.

   The goals of the Industry Day are: (a) to introduce the research
   community
   (industry, academia, and Government) to the Living Foundries vision and
   goals; (b) to encourage and promote teaming arrangements among potential
   research organizations that have the relevant expertise, facilities, and
   capabilities for executing research and development responsive to the
   Living
   Foundries program goals; and (c) to facilitate interaction between
   investigators who may have capabilities to develop elements of interest
   and
   relevance to the Living Foundries goals. The Industry Day will include
   overview presentations, a poster session to facilitate interaction and
   team
   building among participants, and an opportunity to interact and present
   capabilities and concepts to government personnel in closed-door sidebar
   sessions.

   There is no fee for any Industry Day activities. Registration is limited
   by
   the venue capacity (maximum of 100 attendees) and early registration is
   strongly recommended. Organizations are limited to two attendees;
   however,
   in the event that the Industry Day is oversubscribed, DARPA reserves the
   right to limit participation to 1 attendee per organization. The
   registration cutoff date is June 21, 2011, at noon ET, or once attendance
   capacity is met, whichever comes first. An on-line registration form,
   preliminary workshop agenda, citizenship verification form, foreign
   national
   visit request form, meeting details, and hotel information for the
   workshop
   can be found at the following registration website,
   https://safe.sysplan.com/mto/livingfoundries. There will be no on-site
   registration.

   Posters: Appropriate teaming will be a critical element in responding to
   an
   anticipated DARPA Living Foundries solicitation. Industry Day
   participants
   are strongly encouraged to prepare poster abstracts describing areas of
   capabilities in order to facilitate communications, interactions, and
   teaming discussions during the poster session. Poster abstracts must be
   submitted by June 21, 2011, at noon ET. Poster abstracts must include a
   brief (1 page) narrative description of capabilities. Responders may find
   abstract submission guidance at the registration website. Poster
   abstracts
   submitted in response to the Special Notice will be considered public
   information and will be provided on a public website.

   Sidebars: Attendees who wish to describe their capabilities in a
   closed-door
   session with government personnel are required to submit an abstract
   describing their research and capabilities using the guidelines provided
   below; there will be a limited number of sessions depending on schedule,
   with each session lasting no more than ten minutes.

   Areas of interest include new tools, technologies and methodologies to
   transform biology into an engineering practice and manufacturing
   platform,
   decouple biological design from fabrication and speed the biological
   design,
   build, test cycle. Examples include: design tools that span from
   high-level
   description to fabrication in cells; modular genetic parts that allow a
   combination of systems to be designed and reproducibly assembled; methods
   for developing and fine-tuning new genetic parts and systems;
   well-understood test platforms, "cell-like" systems and chassis that
   readily
   integrate new genetic designs in a predictable fashion; next generation
   DNA
   synthesis and assembly techniques; tools that allow for routine system
   characterization and debugging; and the integration of these capabilities
   for the rapid design and development of new biological systems and
   products,
   among others.

   DARPA appreciates responses from all capable and qualified sources
   including
   but not limited to universities, university affiliated research centers,
   and
   private or public companies.

   Sidebar session abstract responses should adhere to the following
   instructions:
   1. All submissions must be made electronically (as described below), and
   be
   in either Adobe PDF or Microsoft Word format.
   2. Cover Page (1 page)
   a. Title
   b. Organization
   c. Responders technical and administrative points of contact (names,
   mailing
   and e-mail addresses, phone and fax numbers)
   3. Technical Ideas (up to 2 pages of text with up to 4 pages of appended
   figures and diagrams)
   a. Executive summary
   b. A discussion of the capability/challenge addressed (from your
   perspective) that is key to realizing the vision of Living Foundries
   c. Technical response. Your discussion should address the following: What
   is
   your proposed innovative technology/concept? How does it address the
   specific capability/challenge that you identified? What is its
   improvement
   over SOA? What extensions or advances are needed to achieve the Living
   Foundries vision?
   4. An optional list of citations, including URLs, if available.
   5. Company brochures and promotional materials are not of interest.

   DARPA will employ an electronic upload process for response submissions.
   NO
   CLASSIFIED INFORMATION SHALL BE INCLUDED IN THE SPECIAL NOTICE (SN)
   ABSTRACT
   RESPONSE. Responses to this SN are due no later than noon ET on June 21,
   2011. Responders may find submission guidance at the registration
   website.

   This SN is issued solely for information and potential new program
   planning
   purposes; the SN does not constitute a formal solicitation for proposals
   or
   proposal abstracts, any so sent will be disregarded. In accordance with
   FAR
   15.201(e), responses to this notice are not offers and cannot be accepted
   by
   the Government to form a binding contract. Submission is voluntary and is
   not required to propose to subsequent Broad Agency Announcements (if any)
   or
   research solicitations (if any) on this topic. DARPA will not provide
   reimbursement for costs incurred in responding to this SN. Respondents
   are
   advised that DARPA is under no obligation to acknowledge receipt of the
   information received, or provide feedback to respondents with respect to
   any
   information submitted under this SN.

   DARPA intends to publish the Living Foundries BAA prior to the scheduled
   Industry Day. However, DARPA is not obligated to publich the BAA prior to
   conducting the Industry Day or to publich an associated BAA at all. If
   and
   when published, the BAA will be made available - at a minimum - on the
   Federal Business Opportunies (FBO) website.

   Questions regarding this event may be directed to
   DARPA-SN-11-44 at darpa.mil.
   Please refer to the "Living Foundries Industry Day" in the subject line.
   Contracting Office Address:
   3701 North Fairfax Drive
   Arlington, Virginia 22203-1714
   Primary Point of Contact.:
   Dr. Alicia Jackson
   DARPA-SN-11-44 at darpa.mil

   - Bryan
   http://heybryan.org/
   1 512 203 0507 <1%20512%20203%200507>

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