<ul><span style="font-weight: bold;">Bryan Bishop <<a href="mailto:kanzure@gmail.com" target="_blank">kanzure@gmail.com</a>></span>
Jun 07 02:26PM -0500
<a href="?ui=2&view=bsp&ver=ohhl4rw8mbn4#1306f1a96c29344f_digest_top">^</a><br>
<br><a href="https://www.fbo.gov/spg/ODA/DARPA/CMO/DARPA-SN-11-44/listing.html" target="_blank">https://www.fbo.gov/spg/ODA/DARPA/CMO/DARPA-SN-11-44/listing.html</a><br>
<br>
Synopsis:<br>
Added: Jun 03, 2011 4:42 pm<br>
Special Notice (SN) DARPA-SN-11-44<br>
SUBJECT: Living Foundries Industry Day<br>
DATE: June 28, 2011<br>
REGISTRATION DEADLINE: June 21, 2011<br>
Registration Website: <a href="https://safe.sysplan.com/mto/livingfoundries" target="_blank">https://safe.sysplan.com/mto/livingfoundries</a><br>
TECHNICAL POC: Dr. Alicia Jackson, DARPA/MTO<br>
<br>
Living Foundries Industry Day, DARPA-SN-11-44<br>
<br>
The Microsystems Technology Office (MTO) of the Defense Advanced
Research<br>
Projects Agency (DARPA) is sponsoring an Industry Day for "Living<br>
Foundries," a new DARPA program. The goal of the Living Foundries
program is<br>
to apply an engineering framework to biology to harness its use as a<br>
technology and drive its advance as a manufacturing platform. In turning<br>
biological production into an engineering space where the only limit is
the<br>
creativity of the designer, Living Foundries aims to enable on-demand<br>
production of new and high-value materials, devices and capabilities for
the<br>
Department of Defense and establish a new manufacturing capability for
the<br>
United States.<br>
<br>
Because of the multidisciplinary nature of Living Foundries, DARPA is<br>
looking to engage the wider research community from fields both outside
and<br>
inside the biological sciences to develop new ideas, approaches and
tools to<br>
overcome current limitations and to create revolutionary capabilities.<br>
<br>
Current, primitive examples of engineering biology rely on an ad hoc,<br>
laborious, trial-and-error process, wherein one successful project does
not<br>
inform subsequent, new designs. This approach combined with the
complexity<br>
of biological systems restricts current, one-off efforts to modifying
only a<br>
small set of genes and constructing simple, isolated genetic circuits
and<br>
metabolic pathways. Consequently, we are limited to producing only a
small<br>
fraction of the vast number of possible chemicals, materials, and living<br>
systems that would be enabled by the ability to truly engineer biology.<br>
Through an engineering-driven approach to biology, Living Foundries aims
to<br>
create a rapid, reliable manufacturing capability where multiple
cellular<br>
functions can be fabricated, mixed and matched on demand and the whole<br>
system controlled by integrated circuitry, opening up the full space of<br>
biologically produced materials and systems. Key to success will be the<br>
democratization of the biological design and manufacturing process,
breaking<br>
open the field to those outside the biological sciences.<br>
<br>
In order to achieve the vision of Living Foundries, new tools,
technologies<br>
and methodologies must be developed to transform biology into an
engineering<br>
practice, decoupling design from fabrication and speeding the biological<br>
design, build, test cycle. These include: design tools that span from<br>
high-level description to fabrication in cells; modular genetic parts
that<br>
allow a combination of systems to be designed and reproducibly
assembled;<br>
methods for developing and fine-tuning new genetic parts and systems;<br>
well-understood test platforms, "cell-like" systems and chassis that
readily<br>
integrate new genetic designs in a predictable fashion; next generation
DNA<br>
synthesis and assembly techniques; and tools that allow for routine
system<br>
characterization and debugging, among others. Further, these
technological<br>
advances and innovations must be integrated to prove-out and push the<br>
boundaries of biological design towards the ultimate vision of
point-of-use,<br>
on-demand, mass-customization biological manufacturing.<br>
<br>
The Industry Day will be held at the Capitol Conference Center in
Arlington,<br>
VA on June 28, 2011. Directions to the Capital Conference Center can be<br>
found at <a href="http://www.thecapitalconferencecenter.com/" target="_blank">http://www.thecapitalconferencecenter.com/</a>.<br>
<br>
The goals of the Industry Day are: (a) to introduce the research
community<br>
(industry, academia, and Government) to the Living Foundries vision and<br>
goals; (b) to encourage and promote teaming arrangements among potential<br>
research organizations that have the relevant expertise, facilities, and<br>
capabilities for executing research and development responsive to the
Living<br>
Foundries program goals; and (c) to facilitate interaction between<br>
investigators who may have capabilities to develop elements of interest
and<br>
relevance to the Living Foundries goals. The Industry Day will include<br>
overview presentations, a poster session to facilitate interaction and
team<br>
building among participants, and an opportunity to interact and present<br>
capabilities and concepts to government personnel in closed-door sidebar<br>
sessions.<br>
<br>
There is no fee for any Industry Day activities. Registration is limited
by<br>
the venue capacity (maximum of 100 attendees) and early registration is<br>
strongly recommended. Organizations are limited to two attendees;
however,<br>
in the event that the Industry Day is oversubscribed, DARPA reserves the<br>
right to limit participation to 1 attendee per organization. The<br>
registration cutoff date is June 21, 2011, at noon ET, or once
attendance<br>
capacity is met, whichever comes first. An on-line registration form,<br>
preliminary workshop agenda, citizenship verification form, foreign
national<br>
visit request form, meeting details, and hotel information for the
workshop<br>
can be found at the following registration website,<br><a href="https://safe.sysplan.com/mto/livingfoundries" target="_blank">https://safe.sysplan.com/mto/livingfoundries</a>.
There will be no on-site<br>
registration.<br>
<br>
Posters: Appropriate teaming will be a critical element in responding to
an<br>
anticipated DARPA Living Foundries solicitation. Industry Day
participants<br>
are strongly encouraged to prepare poster abstracts describing areas of<br>
capabilities in order to facilitate communications, interactions, and<br>
teaming discussions during the poster session. Poster abstracts must be<br>
submitted by June 21, 2011, at noon ET. Poster abstracts must include a<br>
brief (1 page) narrative description of capabilities. Responders may
find<br>
abstract submission guidance at the registration website. Poster
abstracts<br>
submitted in response to the Special Notice will be considered public<br>
information and will be provided on a public website.<br>
<br>
Sidebars: Attendees who wish to describe their capabilities in a
closed-door<br>
session with government personnel are required to submit an abstract<br>
describing their research and capabilities using the guidelines provided<br>
below; there will be a limited number of sessions depending on schedule,<br>
with each session lasting no more than ten minutes.<br>
<br>
Areas of interest include new tools, technologies and methodologies to<br>
transform biology into an engineering practice and manufacturing
platform,<br>
decouple biological design from fabrication and speed the biological
design,<br>
build, test cycle. Examples include: design tools that span from
high-level<br>
description to fabrication in cells; modular genetic parts that allow a<br>
combination of systems to be designed and reproducibly assembled;
methods<br>
for developing and fine-tuning new genetic parts and systems;<br>
well-understood test platforms, "cell-like" systems and chassis that
readily<br>
integrate new genetic designs in a predictable fashion; next generation
DNA<br>
synthesis and assembly techniques; tools that allow for routine system<br>
characterization and debugging; and the integration of these
capabilities<br>
for the rapid design and development of new biological systems and
products,<br>
among others.<br>
<br>
DARPA appreciates responses from all capable and qualified sources
including<br>
but not limited to universities, university affiliated research centers,
and<br>
private or public companies.<br>
<br>
Sidebar session abstract responses should adhere to the following<br>
instructions:<br>
1. All submissions must be made electronically (as described below), and
be<br>
in either Adobe PDF or Microsoft Word format.<br>
2. Cover Page (1 page)<br>
a. Title<br>
b. Organization<br>
c. Responders technical and administrative points of contact (names,
mailing<br>
and e-mail addresses, phone and fax numbers)<br>
3. Technical Ideas (up to 2 pages of text with up to 4 pages of appended<br>
figures and diagrams)<br>
a. Executive summary<br>
b. A discussion of the capability/challenge addressed (from your<br>
perspective) that is key to realizing the vision of Living Foundries<br>
c. Technical response. Your discussion should address the following:
What is<br>
your proposed innovative technology/concept? How does it address the<br>
specific capability/challenge that you identified? What is its
improvement<br>
over SOA? What extensions or advances are needed to achieve the Living<br>
Foundries vision?<br>
4. An optional list of citations, including URLs, if available.<br>
5. Company brochures and promotional materials are not of interest.<br>
<br>
DARPA will employ an electronic upload process for response submissions.
NO<br>
CLASSIFIED INFORMATION SHALL BE INCLUDED IN THE SPECIAL NOTICE (SN)
ABSTRACT<br>
RESPONSE. Responses to this SN are due no later than noon ET on June 21,<br>
2011. Responders may find submission guidance at the registration
website.<br>
<br>
This SN is issued solely for information and potential new program
planning<br>
purposes; the SN does not constitute a formal solicitation for proposals
or<br>
proposal abstracts, any so sent will be disregarded. In accordance with
FAR<br>
15.201(e), responses to this notice are not offers and cannot be
accepted by<br>
the Government to form a binding contract. Submission is voluntary and
is<br>
not required to propose to subsequent Broad Agency Announcements (if
any) or<br>
research solicitations (if any) on this topic. DARPA will not provide<br>
reimbursement for costs incurred in responding to this SN. Respondents
are<br>
advised that DARPA is under no obligation to acknowledge receipt of the<br>
information received, or provide feedback to respondents with respect to
any<br>
information submitted under this SN.<br>
<br>
DARPA intends to publish the Living Foundries BAA prior to the scheduled<br>
Industry Day. However, DARPA is not obligated to publich the BAA prior
to<br>
conducting the Industry Day or to publich an associated BAA at all. If
and<br>
when published, the BAA will be made available - at a minimum - on the<br>
Federal Business Opportunies (FBO) website.<br>
<br>
Questions regarding this event may be directed to <a href="mailto:DARPA-SN-11-44@darpa.mil" target="_blank">DARPA-SN-11-44@darpa.mil</a>.<br>
Please refer to the "Living Foundries Industry Day" in the subject line.<br>
Contracting Office Address:<br>
3701 North Fairfax Drive<br>
Arlington, Virginia 22203-1714<br>
Primary Point of Contact.:<br>
Dr. Alicia Jackson<br><a href="mailto:DARPA-SN-11-44@darpa.mil" target="_blank">DARPA-SN-11-44@darpa.mil</a><br>
<br>
- Bryan<br><a href="http://heybryan.org/" target="_blank">http://heybryan.org/</a><br><a href="tel:1%20512%20203%200507" value="+15122030507" target="_blank">1
512 203 0507</a><br><p> </p></ul><br clear="all"><br>-- <br>P2P Foundation: <a href="http://p2pfoundation.net" target="_blank">http://p2pfoundation.net</a> - <a href="http://blog.p2pfoundation.net" target="_blank">http://blog.p2pfoundation.net</a> <br>
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