[P2P-F] Fwd: [witfor] Why is COVID19 so deadly? From Johns Hopkins Epidemiology

Fri Mar 20 17:55:20 CET 2020

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From: Satish Jha satish.jha at gmail.com [witfor] <witfor at yahoogroups.com>
Date: Fri, Mar 20, 2020 at 11:50 PM
Subject: [witfor] Why is COVID19 so deadly? From Johns Hopkins Epidemiology
To:

Feeling confused as to why Coronavirus is a bigger deal than Seasonal flu?
Here it is in a nutshell. I hope this helps. Feel free to share this to
others who don’t understand...

It has to do with RNA sequencing.... I.e. genetics.

Seasonal flu is an “all human virus”. The DNA/RNA chains that make up the
virus are recognized by the human immune system. This means that your body
has some immunity to it before it comes around each year.... you get
immunity two ways...through exposure to a virus, or by getting a flu shot.

Novel viruses, come from animals.... the WHO tracks novel viruses in
animals, (sometimes for years watching for mutations). Usually these
viruses only transfer from animal to animal (pigs in the case of H1N1)
(birds in the case of the Spanish flu). But once, one of these animal
viruses mutates, and starts to transfer from animals to humans... then it’s
a problem, Why? Because we have no natural or acquired immunity.. the RNA
sequencing of the genes inside the virus isn’t human, and the human immune
system doesn’t recognize it so, we can’t fight it off.

Now.... sometimes, the mutation only allows transfer from animal to human,
for years it’s only transmission is from an infected animal to a human
before it finally mutates so that it can now transfer human to human....
once that happens..we have a new contagion phase. And depending on the
fashion of this new mutation, thats what decides how contagious, or how
deadly it’s gonna be..

H1N1 was deadly....but it did not mutate in a way that was as deadly as the
Spanish flu. It’s RNA was slower to mutate and it attacked its host
differently, too.

Fast forward.

Now, here comes this Coronavirus... it existed in animals only, for nobody
knows how long...but one day, at an animal market, in Wuhan China, in
December 2019, it mutated and made the jump from animal to people. At
first, only animals could give it to a person... But here is the scary
part.... in just TWO WEEKS it mutated again and gained the ability to jump
from human to human. Scientists call this quick ability, “slippery”

This Coronavirus, not being in any form a “human” virus (whereas we would
all have some natural or acquired immunity). Took off like a rocket. And
this was because, Humans have no known immunity...doctors have no known
medicines for it.

And it just so happens that this particular mutated animal virus, changed
itself in such a way the way that it causes great damage to human lungs..

That’s why Coronavirus is different from seasonal flu, or H1N1 or any other
type of influenza.... this one is slippery AF. And it’s a lung eater...And,
it’s already mutated AGAIN, so that we now have two strains to deal with,
strain s, and strain L....which makes it twice as hard to develop a vaccine.

We really have no tools in our shed, with this. History has shown that fast
and immediate closings of public places has helped in the past pandemics.
Philadelphia and Baltimore were reluctant to close events in 1918 and they
were the hardest hit in the US during the Spanish Flu.

Factoid: Henry VIII stayed in his room and allowed no one near him, till
the Black Plague passed...(honestly...I understand him so much better now).
Just like us, he had no tools in his shed, except social isolation...

And let me end by saying....right now it’s hitting older folks harder...
but this genome is so slippery...if it mutates again (and it will). Who is
to say, what it will do next.

Be smart folks... acting like you’re unafraid is so not sexy right now.

#flattenthecurve. Stay home folks... and share this to those that just are
not catching on. 🤓
#reposted

_________________
Satish Jha
Principal,
Ashcroft Sullivan Jha
T:+1 202-286-2006
IN:+91 99100 22922
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Posted by: Satish Jha <satish.jha at gmail.com>
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