A chemist--and social entrepreneur--in Australia is launching an open-source research project to develop a more potent form of a front-line drug against the debilitating neglected tropical disease schistosomiasis. Matthew Todd of the University of Sydney hopes to persuade research chemists across the world to share laboratory time and expertise in a collaborative effort to find a cheap and efficient synthesis of the drug praziquantel. All results will be published in almost real time on the project's Web site--free of intellectual property restrictions--and later in journals, with substantial contributors becoming authors on any resulting papers. Nota completa: http://www.scientificamerican.com/article.cfm?id=open-source-science-disease